Therapeutics of Parkinson's Disease and Other Movement Disorders

Comprehensive evidence-based overview of current therapies for PD and other movement disorders Reviews basic neuropathology, mechanisms of neurodegeneration and principles of pharmacologic intervention. Explores parallels in pathophysiology and aetiology with correlates for therapy Includes surgical intervention and implantable devices for neuromodulation CONTENTS PART I PARKINSONâ ™S DISEASE AND PARKINSONISM. 1 The Etiopathogenesis of Parkinsonâ ™s Disease: Basic Mechanisms of Neurodegeneration (C. Warren Olanow and Kevin McNaught). 2 Physiology of Parkinsonâ ™s Disease (Shlomo Elias, Zvi Israel and Hagai Bergman). 3 Pharmacology of Parkinsonâ ™s Disease (Jonathan M. Brotchie). 4 The Treatment of Early Parkinsonâ ™s Disease (Olivier Rascol and Regina Katzenschlager). 5 Treatment of Motor Complications in Advanced Parkinsonâ ™s Disease (Susan H. Fox and Anthony E. Lang). 6 Managing the Non-Motor Symptoms of Parkinsonâ ™s Disease (Werner Poewe and Klaus Seppi). 7 Surgery for Parkinsonâ ™s Disease (Jens Volkmann). 8 Future Cell- and Gene-Based Therapies for Parkinsonâ ™s Disease (Tomas Bjâ ¬orklund, Asuka Morizane, Deniz Kirik and Patrik Brundin). 9 Parkinson-Plus Disorders (Martin Kâ ¬ollensperger and Gregor K. Wenning). PART II TREMOR DISORDERS. 10 Essential Tremor (Rodger J. Elble). 11 Other Tremor Disorders (Güunther Deuschl). PART III DYSTONIA, CRAMPS, AND SPASMS. 12 Pathophysiology of Dystonia (Mark Hallett). 13 General Management Approach to Dystonia (Cynthia L. Comella). 14 Botulinum Toxin for Treatment of Dystonia (Dirk Dressler). 15 Surgical Treatments of Dystonia (Christopher Kenney and Joseph Jankovic). 16 Wilsonâ ™s Disease (George J. Brewer). 17 Cramps and Spasms (Christine D. Esper, Pratibha G. Aia, Leslie J. Cloud and Stewart A. Factor). 18 Stiff Person Syndrome (Philip D. Thompson and Hans-Michael Meinck). PART IV CHOREA, TICS AND OTHER MOVEMENT DISORDERS. 19 Huntingtonâ ™s Disease (Kevin M. Biglan and Ira Shoulson). 20 Chorea (Francisco Cardoso). 21 Treatment of Tics and Tourette Syndrome (Harvey S. Singer and Erika L.F. Hedderick). 22 Therapeutics of Paroxysmal Dyskinesias (Shyamal H. Mehta and Kapil D. Sethi). 23 Treatment of Miscellaneous Disorders (Marie Vidailhet, Emmanuel Roze and David Grabli). 24 Myoclonus (Shu-Ching Hu, Steven J. Frucht and Hiroshi Shibasaki). PART V DRUG-INDUCED MOVEMENT DISORDERS. 25 Neuroleptic-Induced Movement Disorders (S. Elizabeth Zauber and Christopher G. Goetz). 26 Other Drug-Induced Dyskinesias (Oscar S. Gershanik). PART VI ATAXIA AND DISORDERS OF GAIT AND BALANCE. 27 Ataxia (Thomas Klockgether). 28 Treatment of Gait and Balance Disorders (Bastiaan R. Bloem, Alexander C. Geurts, S. Hassin-Baer and Nir Giladi). PART VII RESTLESS LEGS SYNDROME. 29 The Restless Legs Syndrome (Richard P. Allen and Birgit Hâ ¬ogl). PART VIII PEDIATRIC MOVEMENT DISORDERS. 30 Pediatric Movement Disorders (Jonathan W. Mink). PART IX PSYCHOGENIC MOVEMENT DISORDERS. 31 Psychogenic Movement Disorders (Elizabeth Peckham and Mark Hallett). Index.