Cerebral Small Vessel Disease

Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about its causes, diagnosis, prevention and treatment. This volume brings together contributions from leading international experts in the field and discusses pathogenesis, pathophysiology, clinical and radiologic manifestations, prevention and treatment modalities, and future directions for research and practice. Genetic forms of SVD are discussed, as well as the rapid development of neuroimaging techniques as tools for screening and treatment. This authoritative book is essential reading for neurologists, stroke physicians, geriatricians, and interventional neuroradiologists, as well as researchers in the fields of aging and dementia.

Leonardo Pantoni, MD, PhD is Staff Neurologist, Azienda Ospedaliero Universitaria Careggi, Florence, Italy. Philip B. Gorelick, MD, MPH is Professor of Translational Science and Molecular Medicine, Michigan State University College of Human Medicine, and Medical Director, Hauenstein Neuroscience Center, Mercy Health at Saint Mary's, Grand Rapids, Michigan, USA.