The second edition of Transient Ischemic Attack and Stroke covers the clinical background and management of the full clinical spectrum of cerebrovascular disease, from TIA to vascular dementia, in a compact, but evidence-based format making a comprehensive primer in stroke medicine. Accurate diagnosis and appropriate investigation and management have a major impact on patient outcomes in cerebrovascular disease, such as the effect of urgent antithrombotic treatment on early recurrent stroke after TIA and minor stroke, the effect of interventions such as thrombectomy and hemicraniectomy in major acute stroke, and the effect of stroke units and organised stroke care. Written by a leading team of clinicians and researchers in the field, this book will be essential to neurologists, geriatricians, stroke physicians, allied health workers and all others with an interest in stroke.
A portable yet comprehensive 'handbook' that can be used as a practical reference text during every day practice
Covers recent research, clinical trials, and clinical guidelines in TIA and stroke medicine succinctly, offering an evidence-based primer on the subject
Uniquely offers comprehensive information on the epidemiology and management on minor acute cerebrovascular events
able of Contents
Preface
Part I. Epidemiology, Risk Factors, Pathophysiology and Causes of Transient Ischemic Attacks and Stroke:
1. Epidemiology
2. Risk factors
3. Genetics
4. Anatomy and physiology
5. Pathophysiology of acute cerebral ischemia
6. Causes of transient ischemic attack and ischemic stroke
7. Causes of spontaneous intracranial hemorrhage
Part II. Clinical Features, Diagnosis and Investigation:
8. Clinical features and differential diagnosis of a transient ischemic attack
9. The clinical features and differential diagnosis of acute stroke
10. Brain imaging in transient ischemic attack and minor stroke
11. Brain imaging in major acute stroke
12. Vascular imaging in transient ischemic attack and stroke
13. Non-radiological investigations for transient ischemic attack and stroke
Part III. Prognosis of Transient Ischemic Attack and Stroke:
14. Methods of determining prognosis
15. Short-term prognosis after transient ischemic attack and minor stroke
16. Short-term prognosis after major stroke
17. Long-term prognosis after transient ischemic attack and stroke
Part IV. Treatment of Transient Ischemic Attack and Stroke:
18. Methods of assessing treatments
19. Acute treatment of transient ischemic attack and minor stroke
20. Acute treatment of major stroke: general principles
21. Specific treatments for major acute ischemic stroke
22. Specific treatment of acute intracerebral hemorrhage
23. Recovery and rehabilitation after stroke
Part V. Secondary Prevention:
24. Medical therapies
25. Carotid endarterectomy
26. Carotid stenting and other interventions
27. Selection of patients for carotid intervention
28. Intervention for asymptomatic carotid stenosis
Part VI. Miscellaneous Disorders:
29. Cerebral venous thrombosis
30. Spontaneous subarachnoid hemorrhage
31. Vascular cognitive impairment: epidemiology, definitions, stroke-associated dementia and delirium
32. Vascular cognitive impairment: investigation and treatment.
Gary K. K. Lau is a Clinical Research Fellow at the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford. Sarah T. Pendlebury is an Associate Professor in Medicine and Old Age Neuroscience at the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford. Peter M. Rothwell is an Action Research Professor of Neurology at the University of Oxford, and the Director at the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford.
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