Algorithms provide a logical, concise and cost-effective approach to medical reasoning: utilizing a concise, step-by-step approach based upon clues from the history, physical examination and laboratory studies, algorithms help avoid excessive unnecessary procedures and testing.
The 3rd, revised edition of Practical Algorithms in Pediatric Endocrinology deals with practical issues of child growth, puberty, diseases of the endocrine glands, sexual differentiation, as well as aberrations of water, electrolyte, mineral and carbohydrate metabolism. Fifty-six clinical issues are covered by an algorithmic approach, breaking down long lists and tables of differential diagnosis into smaller, more manageable ones. Common clinical symptoms, signs and laboratory abnormalities are classified as they present themselves at the patient’s bedside.
This book is aimed at general practitioners and pediatricians, in particular those who are not exposed to pediatric endocrine problems on a daily basis, and at trainees in endocrinology and pediatric endocrinology as they acquire familiarity with clinical problem solving to make rational choices when facing clinical dilemmas.
CONTENTS
Growth
2 Undernutrition
E. Gevers; A.D. Rogol
4 Short stature
E. Gevers; A.D. Rogol
6 Growth hormone treatment
E. Gevers; A.D. Rogol
8 Tall stature
E. Gevers; A.D. Rogol
10 Overweight and obesity/
Infantile obesity
A.D. Rogol; E. Gevers
12 Brain irradiation
A.D. Rogol; E. Gevers
Puberty
14 Precocious breast development
in a girl
A.-S. Parent; J.-P. Bourguignon; S. Radovick
16 Precocious genital development
in a boy
J.-P. Bourguignon; A.-S. Parent; S. Radovick
18 Gynecomastia
J.-P. Bourguignon; A.-S. Parent; S. Radovick
20 Delayed or absent testicular
development
S. Radovick; J.-P. Bourguignon; A.-S. Parent
22 Delayed or absent breast
development
S. Radovick; A.-S. Parent; J.-P. Bourguignon
24 Primary amenorrhea
J.-P. Bourguignon; A.-S. Parent; S. Radovick
26 Secondary amenorrhea or
oligomenorrhea
S. Radovick; J.-P. Bourguignon; A.-S. Parent
28 Anovulatory disorders
S. Radovick; J.-P. Bourguignon; A.-S. Parent
30 Hirsutism
S. Radovick; J.-P. Bourguignon; A.-S. Parent
Disorders of sex development
32 Micropenis at age 1 year to puberty
M. Ritzen; P.A. Lee
34 Micropenis in a newborn
M. Ritzen; P.A. Lee
36 Intersex/virilization/hypospadias
M. Ritzen; P.A. Lee
38 Undescended testes/cryptorchidism
in the newborn
P.A. Lee; M. Ritzen
40 Turner syndrome
P.A. Lee; M. Ritzen
42 Klinefelter syndrome
P.A. Lee; C.P. Houk
Adrenal
44 Endocrine hypertension
A. Belgorosky; G.P. Chrousos
46 Hypocortisolism
A. Belgorosky; G.P. Chrousos
48 Precocious pubarche
A. Belgorosky; G.P. Chrousos
50 Cushing syndrome
G.P. Chrousos; A. Belgorosky
52 Congenital adrenal hyperplasia
in the newborn period
A. Belgorosky; G.P. Chrousos
54 Congenital adrenal hyperplasia
presenting after the newborn period
A. Belgorosky; G.P. Chrousos
Water and electrolytes
56 Polyuria
Z. Hochberg; A.D. Rogol
58 Dehydration/hypovolemia
Z. Hochberg; A.D. Rogol
60 Hypernatremia
G.P. Chrousos; A. Belgorosky
62 Hyponatremia
G.P. Chrousos; A. Belgorosky
64 Hyperkalemia
G.P. Chrousos; A. Belgorosky
66 Hypokalemia
G.P. Chrousos; A. Belgorosky
Calcium and bone
68 Hypercalcemia
D. Tiosano; R.I. Gafni
70 Hypocalcemia
D. Tiosano; R.I. Gafni
72 Neonatal hypocalcemia
D. Tiosano; R.I. Gafni
74 Rickets
R.I. Gafni; D. Tiosano
76 Hypomagnesemia
R.I. Gafni; D. Tiosano
78 Fractures
R.I. Gafni; D. Tiosano
Thyroid
80 Hypothyroxinemia
S.A. Rivkees; F. Peter
82 Hyperthyroxinemia
S.A. Rivkees; F. Peter
84 Congenital hypothyroidism
F. Peter; S.A. Rivkees
86 Juvenile hypothyroidism
F. Peter; S.A. Rivkees
88 Hyperthyroidism
F. Peter; S.A. Rivkees
90 Neonatal hyperthyroidism
S.A. Rivkees; F. Peter
92 Goiter
S.A. Rivkees; F. Peter
94 Thyroid nodules in children and
adolescents
F. Peter; S.A. Rivkees
96 Thyroid carcinoma
F. Peter; S.A. Rivkees
Carbohydrates
98 Hypoglycemia in the newborn and
infant
M.A. Sperling; O. Escobar; O. Pinhas-Hamiel
100 Hypoglycemia in the child and
adolescent
M.A. Sperling; O. Escobar; O. Pinhas-Hamiel
102 Hyperglycemia
O. Escobar; M.A. Sperling; O. Pinhas-Hamiel
104 Prediabetes and prediction of
diabetes
O. Escobar; M.A. Sperling; O. Pinhas-Hamiel
106 Type 1 diabetes mellitus
O. Pinhas-Hamiel; M.A. Sperling
108 Type 2 diabetes mellitus
O. Pinhas-Hamiel; M.A. Sperling
110 Monogenic diabetes of the young
O. Pinhas-Hamiel; O. Escobar; M.A. Sperling
112 Diabetic ketoacidosis
O. Pinhas-Hamiel; M.A. Sperling
114 Subject Index
117 Abbreviations
Alicia Belgorosky, MD, PhD
Endocrine Service
Hospital de Pediatria Garrahan
Buenos Aires, Argentina
Jean-Pierre Bourguignon, MD, PhD
CHU Liege, University of Liege
Institut de Formation et de Recherche en
Enseignement Superieur
Liege, Belgium
George P. Chrousos, MD, PhD
University of Athens School of Medicine
‘Aghia Sophia’ Children’s Hospital
Athens, Greece
Oscar Escobar, MD
University of Pittsburgh School of Medicine
Children’s Hospital of Pittsburgh of UPMC
Pittsburgh, Pa., USA
Rachel I. Gafni, MD
Craniofacial and Skeletal Diseases Branch, NIDCR
National Institutes of Health
Bethesda, Md., USA
Evelien Gevers, MD, PhD
The Royal London Hospital – Barts Health NHS Trust
William Harvey Research Institute
London, UK
Ze’ev Hochberg, MD, PhD
Rambam Medical Center
Technion – Israel Institute of Technology
Haifa, Israel
Christopher P. Houk
Georgia Regents University School of Medicine
Augusta, Ga., USA
Peter A. Lee, MD
Pediatric Endocrinology
Penn State Hershey
Hershey, Pa., USA
Anne-Simone Parent, MD, PhD
Pediatric Endocrinology
University of Liege
Liege, Belgium
Ferenc Peter, MD, PhD, DSc
Buda Children’s Hospital and Policlinic
Budapest, Hungary
Orit Pinhas-Hamiel, MD
Safra Children’s Hospital, Sheba Medical Center
Tel Aviv University
Ramat Gan, Israel
Sally Radovick, MD
Department of Pediatrics
The Johns Hopkins University School of Medicine
Baltimore, Md., USA
Martin Ritzen, MD, PhD
Department of Woman and Child Health
Karolinska Institutet
Stockholm, Sweden
Scott A. Rivkees, MD
Shands Children Hospital
Department of Pediatrics, University of Florida
Gainesville, Fla., USA
Alan D. Rogol, MD, PhD
Department of Pediatrics
University of Virginia School of Medicine
Charlottesville, Va., USA
Mark A. Sperling, MD
University of Pittsburgh School of Medicine
Children’s Hospital of Pittsburg of UPMC
Pittsburgh, Pa., USA
Dov Tiosano, MD
Rambam Medical Center
Technion – Israel Institute of Technology
Haifa, Israel
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