The Cutaneous Lymphoid Proliferations

The Cutaneous Lymphoid Proliferations is the go–to reference for a complete, authoritative treatment of the clinical features, phenotype, pathogenesis, histopathology, diagnosis, and treatment of lymphocytic infiltrates of the skin. This second edition incorporates the latest findings from the fields of light microscopy, immunohistochemistry, and flow cytometry and brings readers up to date with the most current thinking in the field.

The book starts off with a clinical atlas and introduction to the ontogeny and biology of the lymphoid system. Next, the authors explore novel molecular approaches to the diagnosis of cutaneous lymphoid proliferation and benign lymphocytic infiltrates. The remaining chapters concentrate on major inflammatory skin diseases and lymphoproliferative disorders, including chronic lymphocytic leukemia, lupus, adult T cell leukemia, and primary cutaneous Hodgkin′s disease.

The title:

–  Discusses additional hematologic dyscrasias, including double hit B cell lymphoma, type D lymphomatoid papulosis, myxoid anaplastic large cell lymphoma, and myeloid dendritic cell leukemia

– Contains brand new content on paraneoplastic cutaneous manifestations of lymphoproliferative disease, and myelomonocytic dyscrasias,  including terminally differentiated histiocytopathies such as Langerhans cell histiocytopathy including Langerhans cell sarcoma and indeterminate cell proliferative disorder

– Covers the role of the immune system in the pathogenesis of cutaneous disease

– Contains numerous new clinical vignettes that clearly show the application of principles and treatment techniques discussed in the chapter

– Discusses the relationships between therapeutic drugs and cutaneous eruptions and carefully notes important drug reactions

– Contains hundreds of full–color, high–quality clinical and histologic photographs, with over 100 new

A classic reference for unsurpassed coverage of lymphocytic infiltrates of the human skin. A masterful and thorough revision of the only single–source, authoritative reference on cutaneous lymphoproliferative disease.

Contents

1 Introduction to the Classification of Lymphoma

2 The Therapy of Cutaneous T Cell Lymphoma
Benjamin H. Kaffenberger, Mark A. Bechtel an Pierluigi Porcu

3 Molecular Analysis In Cutaneous Lymphoid Proliferation
Shabnam Momtahen, Cynthia Magro and Carl Morrison

4 Benign Lymphocytic Infiltrates

5 Reactive Lymphoid Tissue Reactions Mimicking Cutaneous T and B Cell Lymphoma

6 Precursor Lesions of Cutaneous T Cell Lymphoma

7 Marginal Zone Lymphoma And Other Related Post Germinal Center B Cell Lymphoproliferative Disorders of The Skin

8 Primary Cutaneous Follicle Center Cell Lymphoma

9 Primary Cutaneous Diffuse Large B–Cell Lymphoma Including the Leg Type and Precursor B Cell Lymphoblastic Lymphoma

10 Intravascular Lymphoma

11 Cutaneous Mantle Cell Lymphoma

12 Mycosis Fungoides and Sezary Syndrome

13 CD30–Positive Lymphoproliferative Disorders Including Lymphomatoid Papulosis, Borderline CD30–Positive Lymphoproliferative Disease, Anaplastic Large Cell Lymphoma, and T–Cell–Rich CD30–Positive Large B Cell Lymphoma

14 CD4+ Peripheral T Cell Lymphoma Unspecified

15 Subcutaneous Panniculitis–Like T Cell Lymphoma

16 CD8 T Cell Lymphoproliferative Disease of the Skin

17 Nasal and Related Extranodal Natural Killer Cell/T Cell Lymphomas

18 Primary Cutaneous × Ô T Cell Lymphoma

19 Epstein Barr Virus–Associated Lymphoproliferative Disease

20 Primary Cutaneous Hodgkin Lymphoma

21 Chronic Lymphocytic Leukemia of B Cell and T Cell Prolymphocytic Leukemia

22 Adult T Cell Leukemia/Lymphoma

23 Angioimmunoblastic Lymphadenopathy (AILD)/Angioimmunoblastic T Cell Lymphoma

24 Lymphomatoid Granulomatosis (LYG)

25 Cutaneous Infiltrates of Myeloid Derivation

Index 000

Cynthia M. Magro MD
Professor of Pathology and Laboratory Medicine
Department of Pathology, Cornell University
Weill Medical College
New York, USA

A. Neil Crowson MD
Professor of Pathology, Departments of Dermatology, Pathology, and Surgery
University of Oklahoma, and Regional Medical Laboratory
Tulsa, OK, USA

Martin C. Mihm Jr. MD
Professor of Pathology
Department of Pathology
Massachusetts General Hospital and Harvard Medical School
Boston, MA, USA