Molecular Neuropharmacology: A Foundation for Clinical Neuroscience

The definitive guide to treating neurologic and psychiatric disorders with drugs and other approaches

Fully updated with the latest research and drugs, Nestler, Hyman, & Malenka’s Molecular Neuropharmacology, Fourth Edition, is the leading guide to molecular neuroscience. Providing an in-depth look at the neuropharmacological fundamentals of the nervous system, it delivers the knowledge and insight you need to master the pathophysiology of neurologic and psychiatric disorders.

Complete with tables, diagrams, and figures clearly illustrating the intricacies of neurochemistry and molecular neuroscience, this peerless guide reviews the effects of drug action (organized by drug category) to enhance your understanding of major disease mechanisms, and it explains the pathophysiology and neuropharmacology of all major neurologic and psychiatric disorders. Concise overviews of the effects of drugs and other treatment approaches are presented in a way that boosts your understanding and retention of critical concepts.

Nestler, Hyman, & Malenka’s Molecular Neuropharmacology provides a deep dive into:

    General principles of neurophar¬macology
    Nervous system function
    Drugs that act on neuronal and glial function
    Major neurotrans¬mitter systems in the brain and spinal cord
    Atypical neurotransmitters, including peptides, growth factors, and cytokines
    Major brain and spinal cord systems at the molecular, cellular, and circuit levels in health and disease

Contents:

Part 1: Fundamentals of Neuropharmacology

Chapter 1 Basic Principles of Neuropharmacology
Chapter 2 Cellular Basis of Communication
Chapter 3 Synaptic Transmission
Chapter 4 Signal Transduction in the Brain

Part 2: Neural Substrates of Drug Action

Chapter 5 Excitatory and Inhibitory Amino Acids
Chapter 6 Widely Projecting Systems: Monoamines, Acetylcholine, and Orexin
Chapter 7 Neuropeptides
Chapter 8 Atypical Neurotransmitters

Part 3: Neuropharmacology of Neural Systems and Disorders

Chapter 9 Autonomic Nervous System
Chapter 10 Neural and Neuroendocrine Control of the Internal Milieu
Chapter 11 Pain
Chapter 12 Neuroinflammation
Chapter 13 Sleep and Arousal
Chapter 14 Higher Cognitive Function and Behavioral Control
Chapter 15 Mood and Emotion
Chapter 16 Reinforcement and Addictive Disorders
Chapter 17 Schizophrenia and Bipolar Disorder
Chapter 18 Neurodegeneration
Chapter 19 Seizure Disorders
Chapter 20 Stroke and Migraine