Advanced Therapy of Inflammatory Bowel Disease: Crohn's Disease Vol. 2

Now published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal. Theodore M. Bayless, Professor of Medicine and Director Emeritus of the Meyerhoff Inflammatory Bowel Disease Center at Johns Hopkins is the first Sherlock Hibbs Professor in Inflammatory Bowel Disease. A clinician, researcher and an educator, Dr. Bayless has been a member of faculty at Johns Hopkins since 1964 and has provided patient care for over 4000 patients with IBD. Stephen B. Hanauer, MD, is Chief of the Section of Gastroenterology and Nutrition, Director of the Logan Center for GI Clinical Research, and Co-director of the Inflammatory Bowel Disease Research Center at the University of Chicago. Research interests include Diagnosis and treatment of ulcerative colitis and Crohn's disease, screening for cancer in inflammatory bowel disease, general gastroenterology